Japanese encephalitis attacks again: ¿de qué se trata?

Various brotes víricos han hecho que en Australia salten todas las alarmas. The treatment of Japanese encephalitis virus (JEV) broth is in the portions of the New Gales del Sur, Queensland and Victoria, cataloged by the Australian Gobierno as the “national import”.

Have motives for being equipped. The Japanese encephalitis virus represents the most important cause of viral encephalitis in the world and provokes the death of 20,000 annuals. Cause directly and indirectly to the nervous system, for which it is possible to recover from the infection, due to the fact that neurological deterioration is irreversible.

A virus that regresses with the power of every year

Genetic studies suggest that the Japanese encephalitis virus (JEV) evolved originally from a ancestral flavivirus that has been plaguing millennia in the Malayo archipelago region.

Without embargo, the registers of clinics of the virus alone are overhauling the principles of the decade of 1870, when it was written in Japan about the rules of encephalitis in Verano, with substantial incidents that periodically require a rough pace of about 10 days.

Reference photo about cerebral analysis – Photo: Getty Images / Image Source

The example of the great shipwreck was renovated in 1904 and was named “Yoshiwara Fridge” or “Yoshiwara Refrigeration”. The following encephalitis epidemics were reported in 1924, 1935 and 1948. The 1924 issue caused more than 6,000 cases and 3,000 deaths in 6 weeks. Most recently, in the year 2005, the great brothels of Japanese encephalitis were produced in the north of India and Nepal, which accounted for 5,000 cases and 1,300 deaths..

Four million people at risk of infection

As a result of the discovery, the Japanese encephalitis virus has become considerable and now endemic to the mayor of Asia, carrying 4,000 million people at risk of infection. The disease is endemic to 24 countries in Asia, Pakistan has Japan, the north of Australia and Oceania, which is considered to be the most important country in the world.

The annual incidence of Japanese encephalitis is estimated to be at the rate of 69,000 cases, but it is very probable that the figure is supported by the lack of diagnostic tools. Affect fundamentally in children. Someone said that the impact of the accident could be the mayor of the dengue.

For the sake of the males, the weight of the broths in the hemisphere in the western hemisphere is a few communes, the situation is changing. Rapid globalization and climate change are facilitating, respectfully, international journeys and expanding the habitats of the mosquito vectors of the Japanese encephalitis virus. Eso aumenta la probabilidad de que surja la enfermedad en regiones geograficas que anteriormente no estaban afectadas por el virus.

Transmitted by the mosquitoes of the arrozales

The virus that causes the disease is an arbovirus that remains a genus of flavivirus in the flaviviridae family. The principal vectors of the virus are the mosquitoes of the genus Culexespecially Culex tritaeniorhynchus. The vector mosquitoes that transmit prosperity with aspirations in the Asian arthropods. If we end up in endemic areas, we can use an insect repellent, use long mangoes, long pants and vacant pants.

Reference photo about the brain
Reference photo about the brain – Photo: Getty Images

The virus has an amplitude range of vertebrate hues and parece that los cerdos and las aves zancudas actúan como huespedes amplificadores. The virus is circulating in a single enzootic cycle of transmission between mosquitoes, porcine y / o lacustres. The transmission of the disease is more intense than the radiation station, due to the increase in vectors.

The human beings and other species of mammoths, such as the cavallos, are the only ones who are safe, and they do not create the viremia alcanza niveles que sean infekciosos para los mosquitos. Only 1 in 25 and 1 in 1,000 infections in humans produce symptoms. Without embargo, the mortality rate of the symptomatic cases is high, 20-30%, and 30-50% of the experimental experience is neurological and psychiatric significance .

The houses of the grave are characterized by the repentance of apricot fever, cephalea, night stiffness, disorientation, coma, attacks, spastic paralysis and defense.

No hay antivíricos, pero sí vacunas

There are no anti-inflammatory treatments for patients with Japanese encephalitis, but there are certain diseases and effects to prevent illness. In fact, there are a number of types of vacuums against Japanese encephalitis: vacuums of inactivated derivatives of the head of raccoon, vacuums of inactivated derivatives of cultivars of Vero cells, vacuums of attenuated vivas and recombinant vacuums.

The first vacuum is a vacuum of the brain inactivated production in Japan and used in all the world around 50 years. In addition to the production of vacuums of this type, it was announced in 2006, then the production of locally simulated cerebrospinal fluid was inactivated in Corea del Sur, Taiwan, Thailand and Vietnam.

In the last years, in the countries that are endemic, the vacuum living attenuated SA14-14-2, manufactured in China, has been largely used. In Europe alone, the Ixiaro vacuum is available, which contains the SA14-14-2 cepa inactivation of the Japanese encephalitis virus and is produced in Velo cells and posteriorly purified and inactivated.

The estimates show that between the years 2000 and 2019, the precursor vaccination programs in the world of 315,000 cases of Japanese encephalitis and 115,000 deaths due to illness.

Unfortunate, the global climate change affects our present and future in a very different way. Between other things, we offer an opportunity to increase the distribution of Japanese encephalitis to the medium that expands the habitats of the mosquito vectors that make you an endemic animal.

By: Raúl Rivas González

Department of Microbiology, University of Salamanca

The Conversation

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